By Jenny Lelwica Buttaccio*

Quite a few Lyme illness sufferers are turning to CBD (cannabidiol) to assist handle a myriad of signs. From capsules, tinctures, and balms, it’s available in lots of kinds at well being meals shops across the nation. However what’s CBD?

CBD Fundamentals

CBD is one in all a number of elements discovered within the Hashish sativa and indica crops that make up hemp oil. It could include hint quantities of THC, but it surely doesn’t have the psychoactive results of medical cannabis ( marijuana).

In case you’ve been within the Lyme group for any size of time, you’ll hear numerous sufferers sing the praises of this rising compound. Living proof, in a earlier article, I mentioned how I take advantage of CBD  hemp oil to assist ease my insomnia. Right here, I look at 4 further research that display different methods during which CBD could assist mitigate Lyme illness signs.

Science-Backed Makes use of of CBD

1. It lowers anxiousness.

Nervousness is a frequent grievance amongst Lyme sufferers, and plenty of sufferers aren’t glad with the pharmaceutical choices to regulate this situation. A 2015 examine in Neurotherapeutics, a peer-reviewed medical journal, confirmed substantial proof of CBD’s capacity to scale back anxiousness in wholesome people, individuals who have anxiousness problems, or seasonal affective dysfunction (SAD). Moreover, CBD could also be a possible therapy for folks with PTSD and enhance the outcomes of cognitive behavioral remedy (CBT). Nevertheless, the examine factors out that further analysis is required to look at the affect CBD might have with constant use over an extended span of time.

Might we one-day quickly see physicians providing CBD as a therapy possibility for anxiousness? This examine suggests it’s a risk.

2. It’s a pure anti-inflammatory.

Copious quantities of Lyme sufferers battle with persistent ache, and infrequently, they will’t discover an acceptable medicine to alleviate this distressing symptom. At the moment, CBD oil is a scorching subject within the Lyme group, and maybe, rightfully so. Actually, a 2012 examine in Journal of Experimental Medication demonstrated this distinctive compound’s capacity to suppress irritation and nerve ache with out dropping its effectiveness in rodents. For people, this implies CBD, together with different compounds, could also be an progressive Lyme illness therapy technique for individuals who undergo from persistent ache. However in contrast to some conventional ache medicines, you’re unlikely to construct up a tolerance to it.

3. It reduces pimples.

A couple of years in the past I used to be given two medicines from my physician – one to assist me sleep and one other to offer me with vitality. An unlucky facet impact of those prescriptions was that they gave me pimples. Typically, it was the painful, cystic-type of pimples, which will be difficult to deal with. I attempted each cream I might get my fingers on to do away with the breakouts. To my dismay, nothing labored. However in accordance with a 2014 examine in The Journal of Medical Investigation, CBD has the potential to scale back pimples—the most typical pores and skin illness. The examine confirmed that CBD lessened the manufacturing of sebum—an oily substance secreted by the pores and skin’s sebaceous glands. Plus, CBD’s anti-inflammatory properties on the physique helped curtail the incidence of pimples as effectively.

4. It has a neuroprotective impact.

By definition, a neuroprotective substance is one which protects the nerve cells from injury, degeneration, and dysfunction. In Lyme sufferers, the die-off reactions that happen when remedies kill the infections lead to a flood of neurotoxins within the physique. Among the signs of neurotoxicity embrace mind fog, melancholy, dysregulation of hormones, autoimmune situations, insomnia, seizures, and extra. CBD could also be useful for lowering neurotoxicity. In 2003, analysis confirmed CBD had a neuroprotective high quality by blocking the formation of nitrotyrosine – a marker that signifies injury to the cells. Furthermore, the examine confirmed that CBD is a potent antioxidant able to defending the mind from oxidative stress.

Is CBD Authorized?

The 2018 Farm Invoice legalized using cbd derived from hemp in all 50 states. Beforehand, there had been an ongoing, political debate over who managed the substance. The discussions centered round how CBD needs to be categorized. Was it derived from a psychoactive plant (and subsequently, a managed substance)? Or, was it derived from hemp (which didn’t fall beneath the class of a managed substance)?

Lastly, lawmakers reached a consensus on the situations of use for this particular compound. CBD merchandise can legally be bought in shops and on-line and utilized in all 50 states.

Are there uncomfortable side effects from CBD?

The research talked about on this article report that CBD is usually secure and well-tolerated by most individuals. Nevertheless, the long-term results of this compound are unknown right now. CBD is metabolized within the cytochrome p450 pathway of the liver and will probably work together with different medicine that make the most of this pathway (steroids, anti-anxiety medicines, ache medicines, and many others.). Please speak to your physician earlier than incorporating it into your Lyme illness therapy protocol.

Some folks report gentle uncomfortable side effects like tiredness, digest upset, low blood strain, and lightheadedness. However these uncomfortable side effects could fluctuate from person-to-person and by the dosages taken.

Total, the way forward for CBD’s capacity to assist Lyme sufferers seems to be vibrant.

This text was first revealed on ProHealth.com on October 29, 2017 and was up to date on April 9, 2019.


Jenny Lelwica Buttaccio, OTR/L, is a ProHealth editor, author, and occupational therapist. Her life was reworked by Lyme illness, persistent fatigue syndrome and interstitial cystitis. She is creator of the DVD, New Daybreak Pilates: pilates-inspired workout routines tailored for folks with pelvic ache. Jenny is a well being and wellness advocate and blogger who writes about her journey on The Lyme Street as she continues to pursue her private therapeutic with the help of her husband and two rescue pups. Yow will discover her on Instagram: jenny_buttaccio or Twitter: lymeroad.


Blessing, E., Steenkamp, M., Manzanares, J., & Marmar, C. (2015, October 12). Cannabidiol as a Potential Remedy for Nervousness Issues. Neurotherapeutics. 12(4): 825–836. DOI: 10.1007/s13311-015-0387-1

Oláh, A., et al. (2014, April 16). Cannabidiol exerts sebostatic and antiinflammatory results on human sebocytes. The Journal of Medical Investigation. 124(9): 3713–3724. DOI: 10.1172/JCI64628

Xiong, W., et al. (2012, June 4). Cannabinoids suppress inflammatory and neuropathic ache by concentrating on a3 glycine receptors. The Journal of Experimental Medication. 209 (6), 1121. DOI: 10.1084/jem.20120242

El-Remessy, A., et al. (2003, Nov). Neuroprotective Impact of(?)?9-Tetrahydrocannabinol and Cannabidiol in N-Methyl-d-Aspartate-Induced Retinal Neurotoxicity. The American Journal of Pathology. 163(5): 1997–2008. Retrieved from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1892413/